BDBM50248862 CHEMBL473592::N-(3-oxo-3-phenylpropanoyl)-L-homoserine lactone::N-(3-oxo-4-Phenylbutanoyl)-L-homoserine Lactone

SMILES O=C(CC(=O)N[C@H]1CCOC1=O)Cc1ccccc1

InChI Key InChIKey=SZKJWOMSLREKNK-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248862   

TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50248862(N-(3-oxo-4-Phenylbutanoyl)-L-homoserine Lactone | ...)
Affinity DataEC50:  540nMAssay Description:Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTranscriptional activator protein TraR(Agrobacterium tumefaciens)
Universidad De Cartagena-Facultad De Ciencias Exactas Y

Curated by ChEMBL
LigandPNGBDBM50248862(N-(3-oxo-4-Phenylbutanoyl)-L-homoserine Lactone | ...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Agrobacterium tumefaciens TraRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50248862(N-(3-oxo-4-Phenylbutanoyl)-L-homoserine Lactone | ...)
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa LasRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50248862(N-(3-oxo-4-Phenylbutanoyl)-L-homoserine Lactone | ...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed