BDBM50248572 CHEMBL464718::N-hydroxy-1-(3-hydroxypropyl)-2-phenethyl-1H-benzo[d]imidazole-5-carboxamide::US10736881, Compound 40::US8551988, 40

SMILES OCCCn1c(CCc2ccccc2)nc2cc(ccc12)C(=O)NO

InChI Key InChIKey=GVDINOVHHJJJDD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248572   

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248572(CHEMBL464718 | US8551988, 40 | N-hydroxy-1-(3-hydr...)
Affinity DataIC50: 441nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248572(CHEMBL464718 | US8551988, 40 | N-hydroxy-1-(3-hydr...)
Affinity DataIC50: 3.30E+3nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248572(CHEMBL464718 | US8551988, 40 | N-hydroxy-1-(3-hydr...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248572(CHEMBL464718 | US8551988, 40 | N-hydroxy-1-(3-hydr...)
Affinity DataIC50: 3.30E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248572(CHEMBL464718 | US8551988, 40 | N-hydroxy-1-(3-hydr...)
Affinity DataIC50: 441nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent