BDBM50248316 CHEMBL515906::N-hydroxy-3-(2-phenethyl-1H-benzo[d]imidazol-5-yl)acrylamide::US8551988, 50

SMILES ONC(=O)C=Cc1ccc2nc(CCc3ccccc3)[nH]c2c1

InChI Key InChIKey=PPAPPIJCDNZARX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248316   

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248316(CHEMBL515906 | US8551988, 50 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 173nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248316(CHEMBL515906 | US8551988, 50 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed