BDBM50248158 CHEMBL450195::N-butylresorcinol::US8993596, 4-Butylresorcinol (Rucinol)::US9422261, 4-Butyl- resorcinol
SMILES CCCCc1ccc(O)cc1O
InChI Key InChIKey=CSHZYWUPJWVTMQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50248158
Affinity DataIC50: 3.00E+3nMpH: 6.8 T: 2°CAssay Description:The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of mushroom tyrosinase activity after 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of truncated His-tagged human tyrosinase expressed in HEK293 cells using L-DOPA as substrate by MBTH dye based assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.00E+3nMAssay Description:Binding affinity to human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition constant using L-DOPA as substrate by HTS assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair