BDBM50247926 3-(1-benzyl-2-phenethyl-1H-benzo[d]imidazol-6-yl)-N-hydroxyacrylamide::CHEMBL491282::US10201527, Compound 58::US10736881, Compound 58

SMILES ONC(=O)\C=C\c1ccc2nc(CCc3ccccc3)n(Cc3ccccc3)c2c1

InChI Key InChIKey=UCYAZNQZHDVQTA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247926   

TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247926(3-(1-benzyl-2-phenethyl-1H-benzo[d]imidazol-6-yl)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247926(3-(1-benzyl-2-phenethyl-1H-benzo[d]imidazol-6-yl)-...)
Affinity DataIC50: 1.14E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247926(3-(1-benzyl-2-phenethyl-1H-benzo[d]imidazol-6-yl)-...)
Affinity DataIC50: 1.14E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
Go to US Patent