BDBM50247538 CHEMBL4062345

SMILES O=C1COc2ccc(cc2N1)N1CCOC[C@H]1c1ccccc1

InChI Key InChIKey=BTIJTIZKSUGYMC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247538   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247538(CHEMBL4062345)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human GAL4-DBD fused AR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247538(CHEMBL4062345)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at GR (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247538(CHEMBL4062345)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at PR (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247538(CHEMBL4062345)
Affinity DataIC50: 401nMAssay Description:Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247538(CHEMBL4062345)
Affinity DataIC50: 583nMAssay Description:Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed