BDBM50247112 CHEMBL4085633

SMILES C[C@@H](COc1cnc(o1)-c1ccc(Oc2cccc(OCC3CC3)c2)cc1)NC(C)=O

InChI Key InChIKey=FXIMMOHKNCBHMQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247112   

TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247112(CHEMBL4085633)
Affinity DataIC50: 0.960nMAssay Description:Inhibition of recombinant human ACC1 expressed in SF-9 cells preincubated for 60 mins followed by addition of substrate solution containing acetyl-Co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247112(CHEMBL4085633)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant human ACC2 expressed in SF-9 cells preincubated for 60 mins followed by addition of substrate solution containing acetyl-Co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50247112(CHEMBL4085633)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of ACC1 in human HCT116 cells assessed as reduction of [14C]acetate uptake preincubated for 60 mins followed by addition of [14C]acetate a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed