BDBM50247086 CHEMBL444970::Chlorphrifos oxon::diethyl 3,5,6-trichloropyridin-2-yl phosphate

SMILES CCOP(=O)(OCC)Oc1nc(Cl)c(Cl)cc1Cl

InChI Key InChIKey=OTMOUPHCTWPNSL-UHFFFAOYSA-N

Data  2 KI  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50247086   

TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 40nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]CP-55940 from mouse CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]CP-55940 from mouse CB1 receptor expressed in HEK293 cells in presence of mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataKd:  0.860nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brain at 100 nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 10nMAssay Description:Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 460nMAssay Description:Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataIC50: 63nMAssay Description:Displacement of acetylcholine from AChE in Swiss Webster mouse brain after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor DM1(Fruit fly)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]AF-DX 384 from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor DM1(Fruit fly)
University of California

Curated by ChEMBL
LigandPNGBDBM50247086(Chlorphrifos oxon | diethyl 3,5,6-trichloropyridin...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]QNB from Drosophila melanogaster mAChR by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed