BDBM50247074 7-phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-one::CHEMBL461541

SMILES O=C(CCCCCCc1ccccc1)c1nc(co1)-c1ccccn1

InChI Key InChIKey=TYMJNKSRBQAFFG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247074   

TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247074(7-phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247074(7-phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247074(7-phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-o...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50247074(7-phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50247074(7-phenyl-1-(4-(pyridin-2-yl)oxazol-2-yl)heptan-1-o...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed