BDBM50246925 1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine::CHEMBL455699

SMILES Cc1cc(ccc1CNC(=O)Nc1c(F)cccc1F)C(=O)N1CCCCc2ccccc12

InChI Key InChIKey=BWBKKFRRYWSYQR-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246925   

TargetVasopressin V2 receptor(Rat)
Vantia

Curated by ChEMBL
LigandPNGBDBM50246925(1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methyl...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at rat vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVasopressin V2 receptor(Human)
Vantia

Curated by ChEMBL
LigandPNGBDBM50246925(1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methyl...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human vasopressin V2 receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level by CRE-luciferase report...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVasopressin V2 receptor(Human)
Vantia

Curated by ChEMBL
LigandPNGBDBM50246925(1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methyl...)
Affinity DataKi:  200nMAssay Description:Binding affinity to human vasopressin V2 receptor expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxytocin receptor(Human)
Vantia

Curated by ChEMBL
LigandPNGBDBM50246925(1-(4-[3-(2,6-Difluorophenyl)ureidomethyl]-3-methyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed