BDBM50246874 CHEMBL4095643

SMILES COc1ccc(cc1C(=O)Nc1ccc(Cl)cc1)C(=O)NO

InChI Key InChIKey=KNERULXWBNHIGT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50246874   

TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50246874(CHEMBL4095643)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50246874(CHEMBL4095643)
Affinity DataIC50: 310nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50246874(CHEMBL4095643)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed