BDBM50246711 CHEMBL4091934
SMILES COc1cccc(CC[N+](C)(C)C)c1
InChI Key InChIKey=IWYIVUSCDFVNHC-UHFFFAOYSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50246711
Affinity DataEC50: 7.80E+3nMAssay Description:Agonist activity at Gi/o protein-coupled recombinant human muscarinic M2 receptor expressed in CHO-FlpIn cells preincubated for 60 mins followed by [...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Agonist activity at recombinant human muscarinic M2 receptor expressed in HEK293 cells co-expressing beta-arrestin assessed as increase in beta-arres...More data for this Ligand-Target Pair
Affinity DataEC50: 6.30E+3nMAssay Description:Agonist activity at recombinant human muscarinic M2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-mediated cAMP accumulation...More data for this Ligand-Target Pair
Affinity DataEC50: 7.76E+3nMAssay Description:Agonist activity at Gi/o protein-coupled recombinant human muscarinic M2 receptor expressed in CHO-FlpIn cells preincubated for 60 mins followed by [...More data for this Ligand-Target Pair
Affinity DataEC50: 9.10E+3nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M1 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 537nMAssay Description:Agonist activity at recombinant human muscarinic M1 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
Affinity DataEC50: 830nMAssay Description:Agonist activity at recombinant human muscarinic M2 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
Affinity DataEC50: 832nMAssay Description:Agonist activity at recombinant human muscarinic M2 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:Agonist activity at recombinant human muscarinic M1 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.41E+4nMAssay Description:Agonist activity at recombinant human muscarinic M2 receptor expressed in HEK293 cells co-expressing beta-arrestin assessed as increase in beta-arres...More data for this Ligand-Target Pair
Affinity DataEC50: 6.31E+3nMAssay Description:Agonist activity at recombinant human muscarinic M2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-mediated cAMP accumulation...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M3 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.05E+4nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M3 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 9.12E+3nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M1 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Agonist activity at human recombinant muscarinic M2 receptor co-expressed with Galphaqi5-HA in African green monkey COS7 cells assessed as IP accumul...More data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M2 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 9.12E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M2 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M2 receptor expressed in HEK293T cell membranes after 1 hr by liqu...More data for this Ligand-Target Pair
Affinity DataKi: 3.30E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M1 receptor expressed in HEK293T cell membranes after 1 hr by liqu...More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M3 receptor expressed in HEK293T cell membranes after 1 hr by liqu...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M1 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 5.25E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M1 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 8.10E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M3 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataKi: 8.13E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M3 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair