BDBM50246684 CHEMBL503641::N-(1H-indazol-5-yl)acetamide

SMILES CC(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=XGVHKKOLBJMLLQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246684   

TargetProstaglandin G/H synthase 2(Human)
Martin-Luther-Universitaet

Curated by ChEMBL
LigandPNGBDBM50246684(N-(1H-indazol-5-yl)acetamide | CHEMBL503641)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of cyclooxygenase 2 in human whole blood assessed as prostaglandin H2 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Martin-Luther-Universitaet

Curated by ChEMBL
LigandPNGBDBM50246684(N-(1H-indazol-5-yl)acetamide | CHEMBL503641)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of cyclooxygenase 2 in human whole blood assessed as prostaglandin H2 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50246684(N-(1H-indazol-5-yl)acetamide | CHEMBL503641)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50246684(N-(1H-indazol-5-yl)acetamide | CHEMBL503641)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed