BDBM50246600 2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenylsulfonamido)acetic acid::CHEMBL515083

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)CC(=O)NO

InChI Key InChIKey=QVAVQQVTOJMLHH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50246600   

TargetMatrix metalloproteinase-9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 322nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 193nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 213nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 996nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 3.45E+5nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMeprin A subunit beta(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 5.98E+3nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 1.53E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed