BDBM50246599 CHEMBL471537::N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphenyl)ethylcarbamoyl]methyl}-D-valinehydroxamic Acid

SMILES CC(C)[C@@H](N(CC(=O)NCCc1ccc(cc1)S(N)(=O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO

InChI Key InChIKey=GSWRTFGMHRKLKT-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50246599   

TargetMatrix metalloproteinase-9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.210nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 55nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246599(N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataKi:  730nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed