BDBM50246138 2-(2-oxoindolin-5-ylamino)-4-(pyridin-2-ylmethylamino)pyrimidine-5-carbonitrile::CHEMBL470317

SMILES O=C1Cc2cc(Nc3ncc(C#N)c(NCc4ccccn4)n3)ccc2N1

InChI Key InChIKey=NZMLNSPBNGKNHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246138   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246138(2-(2-oxoindolin-5-ylamino)-4-(pyridin-2-ylmethylam...)
Affinity DataIC50: 190nMAssay Description:Inhibition of GST-tagged FAK assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246138(2-(2-oxoindolin-5-ylamino)-4-(pyridin-2-ylmethylam...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed