BDBM50246095 CHEMBL470314::N2-(1-methyl-1H-indol-5-yl)-N4-(pyridin-2-ylmethyl)-5-(trifluoromethyl)pyrimidine-2,4-diamine

SMILES Cn1ccc2cc(Nc3ncc(c(NCc4ccccn4)n3)C(F)(F)F)ccc12

InChI Key InChIKey=WQNZGQPZKQQVSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246095   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246095(N2-(1-methyl-1H-indol-5-yl)-N4-(pyridin-2-ylmethyl...)
Affinity DataIC50: 160nMAssay Description:Inhibition of GST-tagged FAK assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246095(N2-(1-methyl-1H-indol-5-yl)-N4-(pyridin-2-ylmethyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed