BDBM50246059 CHEMBL472211::N4-((1R,2R)-2-Dimethylamino-cyclopentyl)-N2-(1,1-dioxo-2,3-dihydro-1H-1lambda6-benzo[b]thiophen-5-yl)-5-trifluoromethyl-pyrimidine-2,4-diamine

SMILES CN(C)[C@@H]1CCC[C@H]1Nc1nc(Nc2ccc3c(CCS3(=O)=O)c2)ncc1C(F)(F)F

InChI Key InChIKey=BBZHHJCMVZXOQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246059   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246059(N4-((1R,2R)-2-Dimethylamino-cyclopentyl)-N2-(1,1-d...)
Affinity DataIC50: 623nMAssay Description:Inhibition of GST-tagged FAK assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246059(N4-((1R,2R)-2-Dimethylamino-cyclopentyl)-N2-(1,1-d...)
Affinity DataIC50: 67nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed