BDBM50246058 5-(4-(benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)indolin-2-one::CHEMBL471520

SMILES FC(F)(F)c1cnc(Nc2ccc3NC(=O)Cc3c2)nc1NCc1ccccc1

InChI Key InChIKey=SVXALMKNVZGHQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246058   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246058(5-(4-(benzylamino)-5-(trifluoromethyl)pyrimidin-2-...)
Affinity DataIC50: 34nMAssay Description:Inhibition of GST-tagged FAK assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246058(5-(4-(benzylamino)-5-(trifluoromethyl)pyrimidin-2-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of GST-tagged pyk2 assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed