BDBM50245455 9-Hydroxy-6-(2-hydroxyethyl)-4-phenylpyrrolo[3,4-c]-carbazole-1,3(2H,6H)-dione::CHEMBL471156

SMILES OCCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1

InChI Key InChIKey=HFSVLFVYELZPSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245455   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245455(9-Hydroxy-6-(2-hydroxyethyl)-4-phenylpyrrolo[3,4-c...)
Affinity DataIC50: 88nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245455(9-Hydroxy-6-(2-hydroxyethyl)-4-phenylpyrrolo[3,4-c...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed