BDBM50245223 CHEMBL4085483::US11116757, No. A26

SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=WCGOOMQGWKQUSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245223   

TargetDCN1-like protein 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50245223(CHEMBL4085483 | US11116757, No. A26)
Affinity DataIC50: 612nMAssay Description:Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details Article
PubMed
TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
Memorial Sloan Kettering Cancer Center

US Patent
LigandPNGBDBM50245223(CHEMBL4085483 | US11116757, No. A26)
Affinity DataIC50: 163nMAssay Description:The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent