BDBM50245146 6-(3-(1H-imidazol-1-yl)propyl)-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL519238

SMILES Oc1ccc2n(CCCn3ccnc3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1

InChI Key InChIKey=KSTJZQFBPSHFQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245146   

TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245146(6-(3-(1H-imidazol-1-yl)propyl)-9-hydroxy-4-phenylp...)
Affinity DataIC50: 36nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245146(6-(3-(1H-imidazol-1-yl)propyl)-9-hydroxy-4-phenylp...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed