BDBM50244856 CHEMBL461754::rac-(E)-{2-(Hydroxymethyl)-4-[(4-methoxyphenyl)methylene]-5-oxo-1-2,3-dihydrofuryl}methyl 4-methoxybenzoate::rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymethyl)-5-oxo-tetrahydrofuran-2-yl)methyl 4-methoxybenzoate

SMILES COc1ccc(\C=C2/CC(CO)(COC(=O)c3ccc(OC)cc3)OC2=O)cc1

InChI Key InChIKey=PQLKHTRGIRKEMK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50244856   

TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244856(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244856(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50244856(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCalpha expressed in baculovirus expression system after 5 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244856(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  129nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C alpha type(Mouse)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50244856(rac-(E/Z)-(4-(4-methoxybenzylidene)-2-(hydroxymeth...)
Affinity DataKi:  129nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed