BDBM50244088 2-p-Tolyl-4-(4-(2-(2-(trifluoromethyl)-1Hbenzo[d]imidazol-7-yloxy)-ethyl)piperazin-1-yl)-1Hbenzo[d]Imidazole::CHEMBL507973

SMILES Cc1ccc(cc1)-c1nc2c(cccc2[nH]1)N1CCN(CCOc2cccc3[nH]c(=S)[nH]c23)CC1

InChI Key InChIKey=MFKUXMYVLLCVND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244088   

TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244088(2-p-Tolyl-4-(4-(2-(2-(trifluoromethyl)-1Hbenzo[d]i...)
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244088(2-p-Tolyl-4-(4-(2-(2-(trifluoromethyl)-1Hbenzo[d]i...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed