BDBM50243969 CHEMBL452298::N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-[(3,4-dichloro-phenyl)-methyl-amino]-N-methyl-acetamide

SMILES CN(CC(=O)N(C)C(CN1CCOCC1)c1ccc(cc1)-c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ALINQGUROWXGAJ-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243969   

TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243969(N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-[(3,4...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243969(N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-[(3,4...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243969(N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-[(3,4...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243969(N-(1-Biphenyl-4-yl-2-morpholin-4-yl-ethyl)-2-[(3,4...)
Affinity DataKi:  630nMAssay Description:Binding affinity to human urotensin-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed