BDBM50243412 (S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid::CHEMBL499101

SMILES C1CCN(C1)C(=O)[C@H](CC(=O)O)N

InChI Key InChIKey=MGJPXVYXTDEHEJ-UHFFFAOYSA-N

Data  1 KI  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50243412   

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243412((S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid...)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243412((S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243412((S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243412((S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid...)
Affinity DataIC50: 1.22E+5nMAssay Description:In vitro inhibition of human Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243412((S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid...)
Affinity DataIC50: 5.00E+5nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243412((S)-3-amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid...)
Affinity DataKi:  1.45E+4nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article