BDBM50243129 (2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-methylpentan-1-one::CHEMBL502153::US11096924, DASH-inhibitors 5291 (8J)

SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1

InChI Key InChIKey=MMZVCOZOFNZWBM-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50243129   

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 160nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 70nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 5.10E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 4.70E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 7.90E+6nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 3.00E+7nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 1.00E+7nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetHomeobox protein PKNOX1(Human)
Tufts College

US Patent
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 1.00E+8nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM50243129((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Affinity DataIC50: 5.80E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent