BDBM50242781 CHEMBL4083428

SMILES c1cc2c(cnn2[C@@H](CC3CCOCC3)C(=O)Nc4ncc(s4)F)c(c1)S(=O)(=O)C5CC5

InChI Key InChIKey=VFUKAAVEACENGY-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242781   

TargetHexokinase-4(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50242781(CHEMBL4083428)
Affinity DataEC50:  40nMAssay Description:Activation of full length human C-terminal FLAG-tagged glucokinase (12 to 465 residues) expressed in Escherichia coli DH10b using glucose as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)