BDBM50242512 CHEMBL4098682

SMILES Cc1ccc(CNc2nc(N)nc3[nH]c4cc(C)c(O)cc4c23)cc1

InChI Key InChIKey=ITNDOQQPJSLLLO-UHFFFAOYSA-N

Data  1 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50242512   

TargetTyrosine-protein kinase ABL1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of c-Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MARK1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MARK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 2(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEKK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PKC alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetMyotonin-protein kinase(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DMPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of IRAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CK1 alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 21(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50242512(CHEMBL4098682)
Affinity DataKi:  5.67E+3nMAssay Description:Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2019
Entry Details Article
PubMed