BDBM50242138 CHEMBL4099942

SMILES CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(CNC(=O)C[C@H](OC1=O)\C=C\CCC(=O)NO)n2

InChI Key InChIKey=GSYOAHDSQYKHQW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242138   

TargetHistone deacetylase 2(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50242138(CHEMBL4099942)
Affinity DataIC50: 69nMAssay Description:Inhibition of full length C-terminal FLAG-tagged human HDAC2 expressed in baculovirus infected Sf9 insect cells using BPS HDAC substrate 3 after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50242138(CHEMBL4099942)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells using BPS HDAC substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50242138(CHEMBL4099942)
Affinity DataIC50: 600nMAssay Description:Inhibition of full length N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50242138(CHEMBL4099942)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 insect cells using BPS HDAC class 2a substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Duke University

Curated by ChEMBL
LigandPNGBDBM50242138(CHEMBL4099942)
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC10 (1 to 481 residues) expressed in baculovirus infected Sf9 insect cells using B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50242138(CHEMBL4099942)
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed