BDBM50242049 CHEMBL4078716

SMILES COc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1

InChI Key InChIKey=ZONBMEAFHPAAOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242049   

TargetHistone deacetylase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50242049(CHEMBL4078716)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50242049(CHEMBL4078716)
Affinity DataIC50: 314nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50242049(CHEMBL4078716)
Affinity DataIC50: 37nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate incubated for 10 mins followed by substrate addition measured after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details Article
PubMed