BDBM50241779 CHEMBL4082159

SMILES Cl.NC[C@H]1OB(O)c2c1c(Cl)ccc2OCCO

InChI Key InChIKey=FUOKBESTQMGROA-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241779   

TargetLeucine--tRNA ligase, cytoplasmic(Human)
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human N-terminal 6His-tagged cytoplasmic LeuRS expressed in Escherichia coli BL21(DE3) assessed as L-[14C]leucine incorporation in to E...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeucine--tRNA ligase, mitochondrial(Human)
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human N-terminal 6His-tagged mitochondrial LeuRS expressed in Escherichia coli BL21(DE3) assessed as L-[14C]leucine incorporation in to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeucine--tRNA ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)
Affinity DataIC50: 200nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv N-terminal 6His-tagged LeuRS expressed in Escherichia coli BL21(DE3) assessed as L-[14C]leucine incorp...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeucine--tRNA ligase, cytoplasmic(Human)
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)
Affinity DataEC50:  1.37E+5nMAssay Description:Inhibition of cytoplasmic LeuRS in human HepG2 cells assessed as reduction in protein synthesis preincubated for 48 hrs followed by L-[14C]leucine ad...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLeucine--tRNA ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Anacor Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50241779(CHEMBL4082159)
Affinity DataIC50: 216nMAssay Description:Inhibition of Mycobacterium tuberculosis LeuRS expressed in Escherichia coli Rosetta (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed