BDBM50241629 CHEMBL4100348

SMILES OC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)CC(c1ccccc1)c1ccccc1

InChI Key InChIKey=MOKJARNULUKWDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241629   

TargetProtein Mdm4(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50241629(CHEMBL4100348)
Affinity DataIC50: 88nMAssay Description:Inhibition of MDM4 in human SH-SY5Y cells assessed as reduction in MDM4 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50241629(CHEMBL4100348)
Affinity DataIC50: 14nMAssay Description:Inhibition of MDM2 in human U87MG cells assessed as reduction in MDM2 interaction with p53 after 10 mins by quantitative sandwich immune-enzymatic as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed