BDBM50241363 6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL251439

SMILES CC(C)c1cc(Oc2c(C)cc3nc(cc(O)c3c2C)C(O)=O)ccc1O

InChI Key InChIKey=NCPFGULZSPSFGH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241363   

TargetThyroid hormone receptor beta(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50241363(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human TR-beta-1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50241363(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human TR-alpha-1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor beta(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50241363(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...)
Affinity DataIC50: 240nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50241363(6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-4-ox...)
Affinity DataIC50: 617nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed