BDBM50241251 2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfonyl)-amino]-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide::CHEMBL234529::N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphenyl)ethylcarbamoyl]methyl}aminoacetohydroxamic Acid

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)CC(=O)NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=QSOYTCHABFMDFV-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50241251   

TargetMatrix metalloproteinase-14(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 90nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 54nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 532nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 59nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 44nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataKi:  57nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphe...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed