BDBM50241177 (R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide::5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide::CHEMBL226686

SMILES CN(C)C(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO

InChI Key InChIKey=FRASWKFJOBLAQF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241177   

TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177(5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoeth...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human MMP3 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed