BDBM50240964 11-hydroxy-2,3,8,9-tetrahydro-1H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-1-one::2-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::CHEMBL190546

SMILES Oc1ccc2c(c1)[nH]c1c3[nH]c4ccccc4c3c3CNC(=O)c3c21

InChI Key InChIKey=GMSWOSYARKHCHX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240964   

TargetZinc finger protein GLI1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50240964(2-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Gli1-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50240964(2-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50240964(2-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed