BDBM50240932 CHEMBL4092935

SMILES Cn1c(S)nc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=PBFGLXCHNDQITC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240932   

TargetCaspase-3(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of caspase-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCaspase-8(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of caspase-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetLegumain(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 180nMAssay Description:Inhibition of AEP (unknown origin) using Cbz-Ala-Ala-Asn-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetCathepsin S(Human)
Emory Chemical Biology Discovery Center Emory University School of Medicine Atlanta

Curated by ChEMBL
LigandPNGBDBM50240932(CHEMBL4092935)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of cathepsin-S (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed