BDBM50240563 CHEMBL59765::ethyl 2-((S)-8-((R)-2-(3-chlorophenyl)-2-hydroxyethylamino)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yloxy)acetate::{(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy}-acetic acid ethyl ester

SMILES CCOC(=O)COc1ccc2CCC[C@@H](Cc2c1)NC[C@H](O)c1cccc(Cl)c1

InChI Key InChIKey=QFMUIHJMDMGJAY-UHFFFAOYSA-N

Data  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50240563   

TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Dog)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50: >3.20E+3nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Dog)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human cloned beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50: >3.20E+3nMAssay Description:Agonist activity at human cloned beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Dog)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50240563({(S)-8-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylami...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at dog beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed