BDBM50240499 (1R,3aS,5aR,5bR,11aR)-1-Isopropenyl-5a,5b,8,8,11a-pentamethyl-9-oxo-icosahydro-cyclopenta[a]chrysene-3a-carboxylic acid::(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-1-Isopropenyl-5a,5b,8,8,11a-pentamethyl-9-oxo-icosahydro-cyclopenta[a]chrysene-3a-carboxylic acid::3-Oxolup-20(29)-en-28-oic Acid::CHEMBL431525

SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O

InChI Key InChIKey=SLJTWDNVZKIDAU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240499   

TargetG-protein coupled bile acid receptor 1(Human)
Universite Louis Pasteur

Curated by ChEMBL
LigandPNGBDBM50240499((1R,3aS,5aR,5bR,11aR)-1-Isopropenyl-5a,5b,8,8,11a-...)
Affinity DataEC50:  4.71E+3nMAssay Description:Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
The Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50240499((1R,3aS,5aR,5bR,11aR)-1-Isopropenyl-5a,5b,8,8,11a-...)
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of human CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed