BDBM50240415 CHEMBL4078433

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O

InChI Key InChIKey=YBQPTPBTTDQLMD-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50240415   

Target72 kDa type IV collagenase(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 2nMAssay Description:Inhibition of APMA-activated recombinant human MMP2 expressed in CHO cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 50nMAssay Description:Inhibition of APMA-activated recombinant human MMP9 expressed in CHO cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged ADAM10 expressed in baculovirus infected Sf21 cells using Abz-LANAVRSSSR-(DapDnp)-NH2 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ADAM17 expressed in baculovirus infected Sf21 cells using Abz-LANAVRSSSR-(DapDnp)-NH2 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetMeprin A subunit alpha(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of recombinant human meprin alpha expressed in S2 insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of APMA-activated recombinant human MMP13 expressed in mouse NS0 cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetMeprin A subunit beta(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2019
Entry Details Article
PubMed
TargetMeprin A subunit alpha(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of recombinant human meprin alpha expressed in insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMeprin A subunit beta(Human)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50240415(CHEMBL4078433)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed