BDBM50239945 CHEMBL4062686::US9872852, Example 200
SMILES Cc1c(COc2cc(F)c(CNC[C@@H](O)CC(O)=O)cc2F)cccc1-c1ccc2OCCOc2c1
InChI Key InChIKey=UUBRFEROHJGRBO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50239945
Affinity DataIC50: 80nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as reduction in PD-L1/PD1-Ig interaction preincubated with PD-L1 for 15 mins followed ...More data for this Ligand-Target Pair
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to 15N-labeled human PD-L1 (18 to 134 residues) expressed in Escherichia coli BL21(DE3) by 1H-15N 2D HMQC NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of PD-L1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of PDL1 (unknown origin)More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human PD-1/PDL1 by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PD1 (unknown origin)/PDL1 (unknown origin) protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair