BDBM50239780 CHEMBL4065365
SMILES COc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\OCC(O)CO)c2c1
InChI Key InChIKey=GIEDBGFYGHINFT-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50239780
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kaiserslautern
Curated by ChEMBL
University of Kaiserslautern
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of full length human C-terminal His6-tagged CDK2/N-terminal GST-tagged CyclinE expressed in baculovirus infected sf21 cells after 10 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant JAK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant Tyk2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant c-Src (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant Lyn (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant Hck (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant c-Src (unknown origin) incubated for 120 mins in presence of [33P]-ATP by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant JAK1 (unknown origin) incubated for 120 mins in presence of [33P]-ATP by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) incubated for 120 mins in presence of [33P]-ATP by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant TYK2 (unknown origin) incubated for 120 mins in presence of [33P]-ATP by hotspot assayMore data for this Ligand-Target Pair