BDBM50239726 CHEMBL4091840::US10214537, Example 479

SMILES CC(=O)N1CCN(C(=O)C1(C)C)c1cccc(c1)-c1cc(-c2cnc(Cl)n2C)c2c(N)ncnn12

InChI Key InChIKey=FNEXNNPUNHJMRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239726   

LigandPNGBDBM50239726(US10214537, Example 479 | CHEMBL4091840)
Affinity DataIC50: 3nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50239726(US10214537, Example 479 | CHEMBL4091840)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate after 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50239726(US10214537, Example 479 | CHEMBL4091840)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-IgD-mediated B-cell activation by measuring decrease in CD19+ cells expres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed