BDBM50239663 CHEMBL4061729

SMILES COC(=O)c1ccc(s1)-c1cc(cc(c1)[C@]1(C=C(N)Oc2n[nH]c(C)c12)C(C)C)C#N

InChI Key InChIKey=FUAUWFCXVBXZTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239663   

TargetGlycine hydroxymethyltransferase(malaria parasite P. falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239663(CHEMBL4061729)
Affinity DataIC50: 60nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details Article
PubMed