BDBM50239637 CHEMBL4089096

SMILES CN(C)S(=O)(=O)c1ccc(s1)-c1cc(cc(c1)C1(C2CCC2)c2c(C)[nH]nc2OC(N)=C1C#N)C(F)(F)F

InChI Key InChIKey=WJKPOSBCBQYZTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239637   

TargetGlycine hydroxymethyltransferase(malaria parasite P. falciparum)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50239637(CHEMBL4089096)
Affinity DataIC50: 498nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2019
Entry Details Article
PubMed