BDBM50239362 CHEMBL4064865

SMILES [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)N(Cc5ccccc5)c4c(OC\C=C\CO2)c3)n2ncc(Cl)c2n1

InChI Key InChIKey=AFKBQOSFOXILAT-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50239362   

TargetB-cell lymphoma 6 protein(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataIC50: 200nMAssay Description:Inhibition of GAL4 DNA binding domain fused BCL6 BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataEC50:  570nMAssay Description:Agonist activity at 5-HT1B receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GAL4 DNA binding domain fused PLZF BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetB-cell lymphoma 6 protein(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataIC50: 200nMAssay Description:Inhibition of GAL4 DNA binding domain fused BCL6 BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2019
Entry Details Article
PubMed
TargetB-cell lymphoma 6 protein(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataIC50: 11nMAssay Description:Inhibition of human BCL6 BTP domain measured by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetB-cell lymphoma 6 protein(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataIC50: 200nMAssay Description:Inhibition of human BCL6 BTP domain measured by cell reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50239362(CHEMBL4064865)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed