BDBM50239167 CHEMBL1496110
SMILES CCOC(=O)N1CCC(CC1)c1cc(O)n2nc(C)c(-c3ccc(F)cc3)c2n1
InChI Key InChIKey=BFZOZLAMQAIRGP-UHFFFAOYSA-N
Data 8 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50239167
TargetShort transient receptor potential channel 3(Human)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 7.20E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 7(Human)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 1.13E+3nMAssay Description:Agonist activity at human TRPC7 receptor expressed in HEK293 cells assessed as induction of channel current in presence of 0.1 mM Ca2+ by whole cell ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 7(Human)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 497nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 4.66E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as induction of membrane potential de...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Mouse)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataEC50: 4.70E+3nMAssay Description:Agonist activity at mouse TRPC4 expressed in HEK293 cells coexpressing M5 receptor assessed as induction of TRPC4-mediated calcium influx by fluoresc...More data for this Ligand-Target Pair