BDBM50239164 CHEMBL4080748

SMILES CCC(=O)N1CCC(CC1)c1cc(O)n2nc(C)c(-c3ccc(F)cc3)c2n1

InChI Key InChIKey=BWSWSYVPWWFGAR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239164   

TargetShort transient receptor potential channel 6(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239164(CHEMBL4080748)
Affinity DataEC50:  2.88E+4nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 4(Mouse)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc

Curated by ChEMBL
LigandPNGBDBM50239164(CHEMBL4080748)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR decrease in DAMGO-evoked intracellular calcium level by Fluo-8-AM ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed