BDBM50239042 CHEMBL4094511

SMILES CN1C(CCC1=O)c1cc2[nH]c(cc2cc1Oc1ccc(cc1)C(O)=O)-c1ccc(cn1)C(F)(F)F

InChI Key InChIKey=WHOGBCDXUIDCPY-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239042   

TargetHexokinase-4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50239042(CHEMBL4094511)
Affinity DataEC50:  24nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHexokinase-4(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50239042(CHEMBL4094511)
Affinity DataEC50:  2.11E+3nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHexokinase-4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50239042(CHEMBL4094511)
Affinity DataEC50:  9.60nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHexokinase-4(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50239042(CHEMBL4094511)
Affinity DataEC50:  728nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed